Which of the following findings is indicative of increased eosinophilia in asthmatic patients?

The presence of Charcot-Leyden crystals in sputum is indicative of increased eosinophilia, particularly in asthmatic patients. These crystals form from the breakdown of eosinophils, which are a type of white blood cell involved in the inflammatory response, especially in allergic conditions like asthma. When asthma exacerbations occur, there is often an influx of eosinophils into the airways, and their degranulation contributes to the formation of these characteristic crystals.

In patients with asthma, elevated eosinophil levels are associated with more severe inflammation and can lead to worsening symptoms. Therefore, identifying Charcot-Leyden crystals in sputum can help clinicians recognize the underlying eosinophilic activity and guide treatment strategies aimed at managing asthma more effectively.

The other options reflect conditions or findings that do not specifically correlate with eosinophilia in asthmatics. For example, high infection markers typically suggest a bacterial or viral infection rather than an increase in eosinophils, while decreased carbon dioxide levels might indicate hyperventilation or respiratory alkalosis—conditions that may be present in acute asthma exacerbations but are not exclusive or diagnostic for eosinophilia. Lastly, agitation and confusion can result from a variety of issues, such