What is the preferred treatment for both anthrax and Yersinia pestis plague?

The preferred treatment for both anthrax and Yersinia pestis plague is the use of tetracyclines. Tetracyclines, such as doxycycline, are effective against the Gram-positive and Gram-negative bacteria involved in these infections. They work by inhibiting bacterial protein synthesis, which is crucial for bacterial growth and reproduction.

For anthrax, particularly the pulmonary form, early initiation of appropriate antibiotic treatment is vital to reduce mortality. Tetracyclines have been shown to be effective in treating Bacillus anthracis infections. Similarly, for plague caused by Yersinia pestis, particularly in its bubonic and pneumonic forms, tetracyclines have proven efficacy.

While other classes of antibiotics, such as macrolides or fluoroquinolones, may be effective against certain infections, tetracyclines have been firmly established as first-line treatments for these specific pathogens due to their robust efficacy and safety profile. This combination of their effectiveness and the nature of the infections makes tetracyclines the preferred treatment choice for both conditions.